RNA samples from 404 postprostatectomy prostate tumor tissue samples were analyzed by real-time quantitative reverse transcription polymerase chain reaction for the mRNA expression of miR-1207-3p. Patient clinicopathological features and demographic characteristics such as race were identified. A total of 404 patients with primary adenocarcinoma of the prostate were recruited between 19 at the Moffitt Cancer Center, Tampa, FL, USA. In this study, we investigated if miR-1207-3p is capable of distinguishing between indolent and aggressive PCa and if it contributes to explaining the disproportionate aggressiveness of PCa in men of African ancestry (moAA).
MicroRNAs (miRNAs) have been found to be dysregulated in prostate cancer (PCa).